Midlands Extracellular Vesicles Network

Extracellular vesicles

REGISTER TODAY:

Midlands Extracellular Vesicles Network Inaugural Conference – 25th March (Birmingham) – Find out more

 

Mission: Midlands Extracellular Vesicles Network (MEVN) is a joint partnership across the 7 Midlands Innovation Health institutions which aims to:

  1. Develop a vibrant multidisciplinary research community, bringing focus to the diverse Extracellular Vesicle (EV) research activity in the Midlands both academic and industrial.
  2. Facilitate inter-disciplinary and inter-sectoral research collaborations, to develop the next generation of EV based research programmes.
  3. Share best practice and provide a platform for collaborative rather than competitive bids, strengthening submissions to research councils for funding.
  4. Train, support and inspire the next generation of outstanding leaders in EV research.

Collaboration: The partnership structure comprises a senior and early career researcher from each institution:

   Aston University: Professor Andrew Devitt
   University of Birmingham: Dr Joshua Price
   Keele University: Dr Oksana Kehoe and Dr Nicholas Wragg
   University of Leicester: Professor Galina Mukamolova
   Loughborough University: Dr Owen Davies and Dr Soraya Williams
   University of Nottingham: Professor Lucy Fairclough (CHAIR) and Dr Hannah Jackson
   University of Warwick: Professor Dimitris Grammatopoulos and Dr Darius Koester

Support colleagues: Alex Archibald (MI Health), Ellen McGhee (MI) and Matt Vassey (Aston University).

Events: On 21st September 2023, MEVN held an inaugural (half day) virtual conference focussed on ‘Health and Inflammation’. This provided an opportunity for presentations, discussions, and conversations around this exciting and growing area of EV research. To watch recordings from this event click here.

MEVN is looking to run a series of virtual and in-person events. We anticipate these meetings will evolve in content, theme and location as the network grows and would love to engage the community around this as we move forwards. If you are interested in being involved, please get in touch.

 

Midlands Strengths and Capabilities Catalogue
Biology
Biogenesis and secretionNottingham
Cell deathAston
Communication and signalling (intercellular and extracellular)Aston, Nottingham, Nottingham Trent
Complex biofluidsBirmingham, Nottingham Trent
Endothelial cellsAston
EV-enzymatic activitiesNottingham Trent
Epithelial cellsNottingham
Genome stabilityAston
Immune-modulationAston
Immune cellsNottingham
LipidomicsAston
Membranes – biophysics and modelsAston
MetabolomicsAston
Molecular biologyNottingham
Platelet-derived microvesiclesAston
ProteomicsAston, Birmingham, Nottingham, Nottingham Trent
Redox biologyAston
RNABirmingham, Nottingham
Stem cellsAston, Keele, Nottingham
Synthetic and semi-synthetic EVsAston
T cellsKeele
Trypanosomes geneticsWarwick
Applications
AgeingAston
BioinformaticsBirmingham
BiomarkersAston
Cardiovascular diseaseAston
Cancer and cancer therapiesAston, Birmingham, Nottingham
DermatologyLoughborough
Disease pathophysiology, prognosis, and outcomesAston, Birmingham, Nottingham Trent
Drug discoveryAston
DNA damage responsesAston
Exercise and metabolismBirmingham
Hypoxia/normoxia effectsKeele
Inflammation, allergy and allergic sensitisationAston, Keele, Nottingham, Warwick
Lung disease, respiratory infections, COPD, cystic fibrosis and IPFKeele, Nottingham
MaternityWarwick
MusculoskeletalBirmingham, Keele, Loughborough
NanotechnologyAston
NeurologyAston, Nottingham
Regenerative MedicineAston, Keele
TherapeuticsLoughborough
Wound healingAston, Keele
VirologyKeele
Methods
Animal modelsAston, Keele, Nottingham
AssaysAston, Birmingham, Loughborough, Nottingham
Biophysical methodsAston
Cell cycle analysisAston
Cell growth and culturesAston, Keele, Nottingham, Warwick
CentrifugationBirmingham, Keele, Loughborough, Nottingham, Nottingham Trent
Confocal microscopyAston
Cryo-TEMKeele
DNA repair foci analysisAston
ELISAsKeele
ExtractionBirmingham, Keele
Flow cytometryAston, Keele, Nottingham
Freeze-dryingKeele
ImmunopurificationLoughborough
Live cell imagingAston
Lumi-aggregometryAston
Manufacturing and storageKeele
Mass SpectrometryAston, Birmingham, Keele, Nottingham
MicroscopyAston, Nottingham, Nottingham Trent, Warwick
Minimal information for studies of EVsNottingham Trent
Molecular cloningNottingham
Nano Flow CytometryAston, Keele
Nanoparticle tracking analysisBirmingham, Nottingham, Nottingham Trent
Next-generation sequencingKeele, Nottingham
Pathway in vitro reconstitutionsAston
PrecipitationLoughborough
Pulse-field gel electrophoresisAston
Polymerase chain reactionBirmingham, Nottingham, Nottingham Trent
RNA probesNottingham
Single EV quantificationNottingham Trent
Size exclusion chromatographyAston, Birmingham, Keele, Loughborough, Nottingham
Tangential flow filtrationAston, Loughborough
Tunable resistive pulse-sensingAston
UltrafiltrationLoughborough
Western blotAston, Birmingham, Keele, Loughborough, Nottingham, Warwick
X-ray irradiationAston
Equipment
3000 Dionex RS online coupled to 5500 Sciex QTrapAston
5600 Triple TofAston
ABSciex 5500Aston
Agilent Biotek Gen 5Aston
Baker Ruskinn InvivO2 Physiological Cell Culture WorkstationKeele
BD Accuri C6 PlusAston
BD Biosciences FACS Canto II cytometerKeele
Beckman-Coulter CytoflexBirmingham, Keele
Beckman-Coulter Cytoflex SAston
Beckman Coulter L8-M UltracentrifugeKeele
Beckman Coulter Optima TLX UltracentrifugeBirmingham
Beckman Coulter Optima XPN 80 – IVD UltracentrifugeKeele
Bio-Rad pulse field gel electrophoresis systemAston
Christ 1-2 LD plusKeele
Chronolog Model 700Aston
FUJJIFILM Wako MagCapture Exosome Isolation Kit PS Ver.2Warwick
Haematology analyserAston
Hypoxycool unitKeele
Izon automated fraction collectorsAston, Birmingham
Izon ExoidAston, Birmingham
Litesizer 500 for DLSWarwick
Leica confocal microscopyKeele
Malvern LM10, NS300, NS ProBirmingham
Miltenyi MACSPlex exosome kitKeele
Miltenyi Biotec EV Isolation Kit Pan, humanWarwick
Multi-omics on Ascend Tribrid MSAston
NanoFCM NanoanalyseAston
Nanolive Explorer tomographic microscopeAston, Nottingham Trent
Nikon fluorescent microscopeAston
Protein purification chromatography systemsAston
Thermo Scientific™ Q Exactive™ HF-XBirmingham
QIAGEN exoEasy Maxi KitWarwick
Quantum™ Cell Expansion SystemKeele
Unchained Lab Leprechaun/ExoView R100Birmingham, Nottingham Trent
Waters M class online coupled to 5600 Sciex TropleTofAston
ZetaviewNottingham Trent

*Birmingham also have ImageStream and ONI but there are no EV trained individuals

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